Press Release 2013
Hydroxyapatite/collagen nanocomposite-coated titanium rod for achieving rapid osseointegration onto bone surface
Dr. Masanori KIKUCHI (Group Leader) in Bioceramics Group, Biomaterials Unit in MANA, and DDS. Masayoshi UEZONO and Prof. Kazuo TAKAKUDA and Prof. Keiji MORIYAMA in Tokyo Medical and Dental University have developed a new coating to bond bone and titanium three times faster than conventional calcium phosphate coatings.
Subperiosteal devices for orthodontic treatments are superior to screw type devices in viewpoint of lower invasion to our body. The problem is that they require a waiting time of at least 3 months before the treatment can be started even with conventional hydroxyapatite coatings, because the subperiosteal devices should be bonded onto bone surface and not into bone. To reduce this waiting time, the research group has established a new coating method using hydroxyapatite/collagen bone-like nanocomposite (HAp/Col, already approved as a bone filler) that achieves a favorable bone coverage ratio in only one month, in contrast to at least three months that are required in the case of conventional devices.
The method is expected to be conveniently applied to artificial tooth roots and artificial joints as well as the subperiosteal devices for orthodontic treatment.
Subperiosteal devices for orthodontic treatments are superior to screw type devices in viewpoint of lower invasion to our body. The problem is that they require a waiting time of at least 3 months before the treatment can be started even with conventional hydroxyapatite coatings, because the subperiosteal devices should be bonded onto bone surface and not into bone. To reduce this waiting time, the research group has established a new coating method using hydroxyapatite/collagen bone-like nanocomposite (HAp/Col, already approved as a bone filler) that achieves a favorable bone coverage ratio in only one month, in contrast to at least three months that are required in the case of conventional devices.
The method is expected to be conveniently applied to artificial tooth roots and artificial joints as well as the subperiosteal devices for orthodontic treatment.
Further information
Publication/Affiliations
Masayoshi Uezono, Kazuo Takakuda, Masanori Kikuchi, Shoichi Suzuki, Keiji Moriyama, " Hydroxyapatite/collagen nanocomposite-coated titanium rod for achieving rapid osseointegration onto bone surface", Journal of Biomedical Materials Research Part B: Applied Biomaterials, (2013), DOI: 10.1002/jbm.b.32913.
World Premier International Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science (NIMS)
World Premier International Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science (NIMS)
Contact information
For more detail about research
For Material and coating method:
Bioceramics Group, Biomaterials Unit, MANA, NIMS Group Leader Masanori Kikuchi TEL:+81-29-857-6301 E-mail: KIKUCHI.Masanori@nims.go.jp
For Device:
Medical and Dental Device Technology Incubation Center, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Professor Kazuo Takakuda TEL: 03-5280-8040 E-mail: takakuda.mech@tmd.ac.jp
For Orthodontic treatments:
Department of Maxillofacial Orthognathics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Professor Keiji Moriyama, TEL: 03-5803-5532 E-mail: k-moriyama.mort@tmd.ac.jp
Bioceramics Group, Biomaterials Unit, MANA, NIMS Group Leader Masanori Kikuchi TEL:+81-29-857-6301 E-mail: KIKUCHI.Masanori@nims.go.jp
For Device:
Medical and Dental Device Technology Incubation Center, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Professor Kazuo Takakuda TEL: 03-5280-8040 E-mail: takakuda.mech@tmd.ac.jp
For Orthodontic treatments:
Department of Maxillofacial Orthognathics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Professor Keiji Moriyama, TEL: 03-5803-5532 E-mail: k-moriyama.mort@tmd.ac.jp
For general inquiry
Public Relations Office, NIMS
Email: prnims.go.jp
TEL:+81-29-859-2026 FAX:+81-29-859-2017
Email: prnims.go.jp
TEL:+81-29-859-2026 FAX:+81-29-859-2017