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NewsNews 2022

Tomohiro Murata and Katsuhiko Ariga Appeared in "NIMS Hot Article"

23 Dec, 2022
(23 Dec, 2022 Update)

Detection of trace amounts of water through solvent vapors!
—Gas sensor replaces Karl Fischer titration for trace water determination.—

Focusing on the property of DNA to swell when it hydrates with trace amounts of water, we developed a sensor to detect trace amounts of water in organic solvents (less than one part per million concentration) by measuring their vapors.

This sensor realizes simple, non-contact, and real-time detection/monitoring of trace water, which has been limited to measurement in liquids such as Karl Fischer titration.

This work was made by a collaborative work between NIMS and The University of Tokyo.

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reseacher's photo

Tomohiro Murata


reseacher's photo

Katsuhiko Ariga



Article Information

Title Detection of Trace Amounts of Water in Organic Solvents by DNA-Based Nanomechanical Sensors
Journal Biosensors
Author Tomohiro Murata, Kosuke Minami, Tomohiko Yamazaki, Genki Yoshikawa, and Katsuhiko Ariga
Date December 1, 2022
DOI 10.3390/bios12121103


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