Focusing on the property of DNA to swell when it hydrates with trace amounts of water, we developed a sensor to detect trace amounts of water in organic solvents (less than one part per million concentration) by measuring their vapors.

This sensor realizes simple, non-contact, and real-time detection/monitoring of trace water, which has been limited to measurement in liquids such as Karl Fischer titration.

This work was made by a collaborative work between NIMS and The University of Tokyo.

■ Related Information
- NIMS Hot Article
Detection of trace amounts of water through solvent vapors!
—Gas sensor replaces Karl Fischer titration for trace water determination.—

■ Article Information
"Detection of Trace Amounts of Water in Organic Solvents by DNA-Based Nanomechanical Sensors"
Tomohiro Murata, Kosuke Minami, Tomohiko Yamazaki, Genki Yoshikawa, and Katsuhiko Ariga
Journal : Biosensors [December 1, 2022]
DOI : 10.3390/bios12121103