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Press ReleasePress Release 2010

Identification of Nucleic Acid Bases that Cannot be Distinguished by DNA (Uracil, Thymine) Achieved Using Hand-Operating Nanotechnologyh

14 Oct, 2010

An synthetic membrane with the ability to identify the genetic code (nucleic acid bases) uracil (U) and thymine (T) at greater than 60 times sensitivity has been developed. Even DNA is unable to distinguish these two genetic codes.
Figure 1, Hand-operating nanotechnology

Figure 1. Discrimination of uracil and thymine by Hand-Operating Nanotechnology.

Figure 2, Binding curve and bring model

Figure 2. Binding curve (left) and bring model (right)

Further information

Affiliations

Taizo Mori1, Ken Okamoto1, Hiroshi Endo1, Jonathan P. Hill1,2, Satoshi Shinoda2,3, Miki Matsukura3, Hiroshi Tsukube1,3, Yasumasa Suzuki 4, Yasumasa Kanekiyo4, Katsuhiko Ariga1,2
  1. International Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science (NIMS)
  2. JST, CREST
  3. Osaka City University
  4. Kitami Institute of Technology

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