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	Biology area

Nanosearch Microscope

Manufaturer： Olympus/Shimadzu Model： OLS3500/SFT-3500 Intended use： Observe from mili-meter to nano-meter with this combined system of laser conforcal microscope (LCM) and scanning probe microscope (SPM). 　Specification Optical lenses 5x、20x、100x LCM movement resolution (vertical) 10nm SPM scanning range XY=30um, Z=2um SPM detection Optical lever（premount with canti-lever alighnment system） SPM mode contact, dynamic, phase

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Microarray scanner

Manufacturer： Agilent Model： SureScan 4900DA Intended use： Measure fluorescence of microarray. 　Specification Samples standard microscope slide Scan area max 22 x 71.5 mm Excitation 532 nm and 635 nm Emission filters Optimized for Cy3 and Cy5

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Biacore

Manufacturer： GE Healthcare Model： BIACORE-X100 Intended use： Detect biomolecular interactions real-time and label-free with surface plasmon resonnance technology. 　Specification dissociation constant 100 μM to 1 pM Detection limit About 0.1 nM for > 10^4 Da analytes, about 1 nM for < 10^4 Da analytes Injection volume 5–90 μL Molecular weight detection Down to 100 Da in various sample environments

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Real time PCR

Manufacturer： Roche Model： Lightcycler 480SystemII Intended use： Detect gene, analyse gene expression or genetic variation and validate array data. 　Specification Temparature range 37℃～95℃ Optics Exitation wave length（nm）： 440, 465, 498, 533, 618 Detection wave length（nm）： 488, 510, 580, 610, 640, 660

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Gel imager

Manufacturer： kurabo Model： Dolphin-Doc Intended use： Photograph and analyze gel electrophoresis patterns of DNA, RNA or protein. 　Specification

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Gradient PCR

Manufacturer： Takara bio Model： TaKaRa PCR Thermal Cycler Dice GradientTP600 Intended use： Determine conditions of PCR. 　Specification Temp. range 4℃～99.9℃（per 0.1℃） Gradient temp. range 40～75℃（temprature width 6～20℃）

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PCR

Manufacturer： Takara bio Model： TaKaRa PCR Thermal Cycler Dice Standard TP650 Intended use： Amplify DNA fragments. 　Specification Temp. range 4℃～99.9℃（per 0.1℃）

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Spectrophotometer

Manufacturer： Thermo Model： NanoDrop 2000 Intended use： Measure absorbance spectrum of liquid samples. 　Specification Wave length range 190～840nm minimum volume 0.5μL

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Table top SEM

Manufacturer： Hitachi-hightech Model： Miniscope TM3000 Intended use： Obsearve samples without complex processing. 　Specification magnification 15x～30,000x EDS detect B5 to Am95

Cell analyzer

Manufacturer： SONY Model： Spectral cell analyzer SP6800 Intended use： Characterize cells with fluarescence and scattering. 　Specification Laser 488nm/638nm Spectroscopy prism array Fluorescence range 500nm-800nm（32channels） Detection size 0.5～40μm　（beads）

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Cell sorter

Manufacturer： SONY Model： Cell sorter SH800 Intended use： Sort cells according to their character. 　Specification Lasers 405, 488, 561, 638(nm) Detection channels 1 × FSC, 1 × BSC, 6 × Fluorescece

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	Bio-imaging area

Laser microdissection system

Manufacturer： Leica microsystems Model： LMD7000 Intended use： Obtain pure samples from heterogeneus tissue sample or cell culture by dissecting them with high power laser. 　Specification　 Laser Diode pumped, solid state, 349nm Objective lense 1.25ｘ6.3ｘ10ｘ20ｘ40ｘ Microscope upright microscope, bright field Stage precision ± 2 μm Dissection modes Draw & Cut, Move & Cut (direct online cutting), Draw & Scan (dot dissection scan)

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Live cell imaging ＆ TIRF

Manufacturer： Leica microsystems Model： AF6000LX＋AM TIRF Intended use： Obsearve fluorescence, DIC and TIRF. Also obsearve cells continuously with built-in cell culture system. 　Specification　 Lenses 10ｘ40ｘ63ｘ(Gly)100xTIRF Others Super Z galvanostage、external filter wheels、cooled CCD camera

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Confocal laser scanning fluarescence microscope

Manufacturer： Leica microsystems Model： TCS SP5 Feature： Microscope for fluorescence imaging. With conforcal system, high-speed image capturing or high resolution imaging is possible. 　Specification objective lenses 10ｘ20ｘ40ｘ63ｘ high-speed imaging 250 frames /sec high-resolution imaging maxmum 8000×8000 pixels

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Laser raman microscoppe

Manufacturer： Nanophoton Model： RAMANplus Feature： High speed raman imaging and surface measurement. Line illumination and laser beam scanning enables ultra-fast Raman imaging. 　Specification Microscope Nikon Laser 532nm Detector TE-cooled CCD 1340 × 400 pixel format raman field range：90×120um spatial resolution　X-axis：350nm, Y-axis：800nm spectral resolution：1.6cm-1 raman-shift range：80 ～ 4000cm-1 （note）with x100 0.9NA objective lense and 1200/mm grating

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Digital microscope

Manufacturer： Leica microsystems Model： DMD108 Feature： Having microscope, PC and digital camera into one body, this system is suitable for discussions observing microscope images. 　Specification observation blight field objective lenses 4ｘ10ｘ20ｘ40ｘ light source LED focus manual digital camera maxmum 2048×1536 pixels

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Stereomicroscope with digital camera

Manufacturer： Leica microsystems Model： MZ16＋DFC290 Feature： This is high resolution stereo microscope with apochromatic optical system. 　Specification Zoom 16.2:1 magnification 7.1x-115x resolution maxmum 420 Lp/mm Color digital camera 300x10^4 pixels (2048x1536), exposure time 0.1 msec～2.0 sec interface FireWire(IEEE1394a)

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Stereomicroscope with digital camera

Manufacturer： Leica microsystems Model： S8 APO＋EC3 Feature： Greenough stereomicroscope with a fully apochromatic corrected 1.0x objective and zoom lens system. 　Specification　 zoom 8:1 magnification 10x-80x digital camera 310x10^4 pixels interface USB2.0, C mount adaptor

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Fluorescence microscope (with differential interference contrast)

Manufacturer： Leica microsystems Model： DM2500 Fluo/DIC Feature： Upright microscope for fluorescence, differential interference contrast and bright field observation. Images can be taken by color digital camera. 　Specification observation Bright field/Fluorescence/Differential interference contrast objective lenses 10ｘ20ｘ40ｘ100ｘOil（FL PLAN) digital camera Leica DFC300fx for fluorescence

Fluorescence microscope（with phase contrast)

Manufacturer： Leica microsystems Model： DM2500 Fluo/PH Feature： Upright microscope for fluorescence, phase contrast and bright field observation. 　Specification observation Bright field/Fluorescence/Phase contrast objective lenses 10ｘ20ｘ40ｘ100ｘOil（FL PLAN)

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Cryostat

Manufacturer： Leica microsystems Model： CM1850 Intended use： Cut frozen tissue specimen for optical microscope observation. 　Specification section thickness 1～60μm holizontal movement 25mm, 2speeds（Slow 0.2mm/s、Rapid 0.7mm/s） triming motorized coarse feed maxmum sample size 55mmφ cutting manual handle chamber temperature 0℃～－35℃（room temp. 22℃） freezing shelf －40℃

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	Cell culture room

CO2incubator

Manufacturer： SANYO (Panasonic) Model： LMD6000 MPP Intended use： Incubate cell culture 　Specification temperature room temp. ＋5℃～55℃

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Clean chamber

Manufacturer： Yamato scientific Model： ADS131 Intended use： Provide clean environment for cell culture manipulations.

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Microscope for cell culture

Manufacturer： Leica microsystems Model： DMIL-TR/EC3 Intended use： Observe cell culture 　Specification observation BF/PH objective lenses 5ｘ10ｘ20ｘ40ｘ camera 310x10^4 pixels digital camera interface USB2.0, C mount adaptor

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	Analysis area

FT-IR

Manufacturer： Shimadzu Model： IRTracer-100 Intended use： Analyze molecular structure 　Specification spectro range 7,800～350cm-1（depend on attachment） resolution maxmum 0.25cm-1 SN maxmum 60000:1

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MALLS and GPC

Manufacturer： Shodex (GPC) Model： GPC101 Intended use： Separate molecules by their size Manufacturer： Wyatt (MALLS) Model： DAWN Heleos Intended use： Determine molecule size

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Laser zeta potential

Manufacturer： Otsuka electronics Model： ELSZ-1000Z Intended use： Evaluate dispersion stability of particles in solvent 　Specification zeta potential range -200mV～200mV cell standard, micro(130ul) and flat state sample cell

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Laser particle size analyzer

Manufacturer： Shimadzu Model： SALD-2100 Intended use： Determine particle size distribution of granule or powdered samples 　Specification range 0.03μm～1000μm light source diode laser（680nm)

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Circular dichroism spectrometer

Manufacturer： Jasco Model： J-725型 Intended use： Analyse secondary structure of proteins or determine chirality of molecules 　Specification wave length 165～1100nm range 0～5Abs

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Texture analyzer

Manufacturer： Eiko Model： TA-XT2i Intended use： Analyze texture 　Specification test bed size 280ｍｍ x 395mm test bed hight 660mm key board size 220mm x 433mm

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Dynamic light scattering (DLS)

Manufacturer： Otsuka electronics Model： DLS-8000HAL Intended use： Measure particle size 　Specification range 1.4nm～7μm range (molecular weight) 300～2×107Ｍw light source He-Ne Laser（632.8nm） solid state blue laser（488nm）

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Spray dryer

Manufacturer： BUCHI Model： B-290 Intended use： Dry solutions, emulsions etc. Transform a fluid state sample into a dried particulate form by spraying the feed into a hot drying medium. 　Specification heater 2300W spray gas air or N2 200-1000L/h, 5-8bar air flow max. 35m3/h feed rate max. 1.0L/h nozzle diameter 0.7mm Mean residence time 1.0～1.5sec

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Plasma cleaner

Manufacturer： Yamato Scientific Model： PDC200 Intended use： Removal of organic films, surface cleaning, surface reforming, surface etching etc. 　Specification plasma mode RIE electrode parallel flat stage plate radio-frequency output power 100～300W oscillating frequency 13.56MHz sample chamber aluminum plasma gas oxygen purge gas N2 or air

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Gas chromatograph

Manufacturer： Shimadzu Model： GC-2010 Intended use： Analyze vaporized compounds by gas phase chromatograph. 　Specification temperature room temp. +4℃～450℃ detector flame ionization detector(FID) and thermal conductivity detector(TCD) dynamic range 107(FID) or 105(TCD) carrier gas pressure range 0-970kPa

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LC-MS/MS(LXQ)

Manufacturer： AMR Model： ZAPLOUS LC/MS system Intended use： Identify proteins by separating and analyzing their enzymatically digested peptides.

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LC-MS/MS (Q-Exactive)

Manufacturer： AMR Model： Zaprous ADV Q-Exactive system Intended use： Analyze samples with high-resolution and measure accurate mass. 　Specification mass spectorometer Q-Exactive plus hybrid quadrupole-orbitrap LC Bruker michrom nano-Advance UHPLC protein identification software MASCOT other weekly updating the protein database automated analysis with robot arm sample charge system

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GPC

Manufacturer： TOSO Model： HLC-8220GPC Intended use： Analyze molecular sizes with gel permeation chromatograph. 　Specification liquid derivering paralel flow rate 1～2,000μl/min sample vol. 1～1,500μl temparature room temp.+10℃～100℃, accuracy:±0.5℃ detector light source tungsten lamp dynamic range 5×10-4RIU

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Double beam spectrophotometer

Manufacturer： Hitachi high-tech Model： U-2900 Intended use： Measure UV-VIS absorption spectra of materials. 　Specification Wavelength range 190～1100nm Spectral bandpass 1.5nm

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Fluorescence spectrophotometer

Manufacturer： Hitachi high-tech Model： F-7000 Intended use： Measure fluorescence spectra of materials. 　Specification sensitivity raman light of water S/N800 or above, S/N250 or above Measuring wavelength range (on both EX and EM) 200～750nm Wavelength scan speed 30, 60, 240, 1,200, 2,400, 12,000, 30,000, 60,000 nm/min

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Recycling preparative GPC

Manufacturer： Japan analytical industry Model： LC-9201 Intended use： Purify synthesized compound by column chromatography. 　Specification maxmum flow 9.9ｍｌ/mL

Contact angle meter

Manufacturer： AST PRODUCTS Model： VCA Optima-XE Intended use： Characterize material's surface by measuring contact angle of liquid. 　Specification functions measurement of dynamic or static contact angle inspection of surface wettability and cleanliness evaluation of surface processing or coating evaluation of adhesive property analysis of surface free energy analysis of surface tension

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NMR

Manufacturer： JEOL Model： ECS-400 Intended use： Determine molecular structure by measuring nuclear magnetic resonance. 　Specification observation frequency 1H 400MHz observation nuclei 1H, 13C, 15N, 31P etc. Auto sample changer 16 samples

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	Organic chemistry area

Anaerobic glove-box

Manufacturer： MBRAWN Model： Unilab Intended use： Use as unaerobic reaction chamber.

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NIMS分子・物質合成プラットフォーム事務局 〒305-0047　茨城県つくば市千現1-2-1 TEL：029-859-2399