Research Topics 2010
A New Promise for Cardiac Repair
- Tissue Engineering Using Stem Cells and Biocompatible Scaffolds –Nov 24, 2010
- This research was conducted by
- Fuel Cell Nano-Materials Group (headed by Enrico Traversa MANA PI)
A novel approach for cardiac tissue engineering has been successfully developed. Complete maturation of adult murine cardiac resident progenitor cells (CPC) towards cardiac phenotype was induced within few days by the cooperation of biological and mechanical stimuli, giving promise for patient novel treatments.
Left: Exploded view of the 3D biodegradable scaffold made of PLA (left).
Center: SEM micrograph of a CPC stretched bridging over the pore window.
Right: Immuno-fluorescence microscope image showing cell nuclei (blue) and cytoskeletal sarcomeres (red) of fully differentiated CPCs over the 3D scaffold.