イベント
第161回先端計測オープンセミナー
電子顕微鏡動画撮影による映像分子科学の探究
原野 幸治 主幹研究員、電子顕微鏡グループ
2022年6月30日 (木) 16:00~17:00
会場/Venue：
千現地区 研究本館8階中セミナー室（811・812室）＋オンライン（Zoom）
Sengen Central Bldg. 8F Meeting Room 811,812 + Online (Zoom）
Sengen Central Bldg. 8F Meeting Room 811,812 + Online (Zoom）
参加登録/Registration：
会場参加、オンライン参加を問わず、参加登録をお願いいたします。
登録はこちら
オンライン参加の接続URLは、登録が済まれた方に後日お知らせ致します。
Please register for both on-site and online participation.
Click here to register
Those who have registered will be notified of a connection URL for online participation later.
登録はこちら
オンライン参加の接続URLは、登録が済まれた方に後日お知らせ致します。
Please register for both on-site and online participation.
Click here to register
Those who have registered will be notified of a connection URL for online participation later.
講演者/Speaker：
原野 幸治 電子顕微鏡グループ 主幹研究員
HARANO.Koji, Principal Researcher, Electron Microscopy Group
HARANO.Koji, Principal Researcher, Electron Microscopy Group
表題/Title：
電子顕微鏡動画撮影による映像分子科学の探究
Cinematic molecular science explored by electron microscopic video imaging
Cinematic molecular science explored by electron microscopic video imaging
概要/Abstract
高空間・時間分解能顕微鏡技術の進歩により、有機、無機材料を構成する分子の動的挙動を実時間の映像を通して研究できる「映像分子科学」の時代が到来した。我々は単分子原子分解能時間分解電子顕微鏡法（SMART-EM）により、分子の構造変換や分子集合の過程、さらには化学反応やメカニカル運動など、確率論的に起こる分子のダイナミクスを多くの分子の平均像としてではなく１分子ごとにとらえ、解析することを実現した。本セミナーでは、SMART-EMによる単分子撮像手法の原理、および様々な物質を対象とした化学研究への応用展開について紹介する。
Advances in microscopy with high spatial- and time-resolution have ushered in the era of “cinematic molecular science", in which dynamic behaviors of organic and inorganic molecules can be studied through real-time cinematographic images. We established a method named single-molecule atomic-resolution time-resolved electron microscopy (SMART-EM) for observation of stochastic molecular dynamics, such as structural transformation, molecular assembly processes, chemical reactions, and nanomechanical motions on a single molecule basis. This method allows us to understand the behavior of molecules as statistics of observations of individual molecules, which could only be studied as an averaged information of many molecules in conventional chemical analysis. In this seminar, I will introduce the principle of SMART-EM imaging and its application to chemical research of various materials.
Advances in microscopy with high spatial- and time-resolution have ushered in the era of “cinematic molecular science", in which dynamic behaviors of organic and inorganic molecules can be studied through real-time cinematographic images. We established a method named single-molecule atomic-resolution time-resolved electron microscopy (SMART-EM) for observation of stochastic molecular dynamics, such as structural transformation, molecular assembly processes, chemical reactions, and nanomechanical motions on a single molecule basis. This method allows us to understand the behavior of molecules as statistics of observations of individual molecules, which could only be studied as an averaged information of many molecules in conventional chemical analysis. In this seminar, I will introduce the principle of SMART-EM imaging and its application to chemical research of various materials.