2025

• Exploring anti-cancer activities of epidermal growth factor-immobilized polymeric nanoparticles.

  Shota Yamamoto, Chia-Jung Chang, Masao Kamimura, Jun Nakanishi.
  Science and Technology of Advanced Materials. 26 [1] (2025) 2463316 10.1080/14686996.2025.2463316

• Potential-Switchable Viscoelasticity of Protein Nanolayers at a Liquid/Liquid Interface.

  Kosuke Ishii, Takeshi Ueki, Jun Nakanishi, Kazuhiro Akutsu-Suyama, Norifumi L. Yamada, Yuko Yokoyama, Tetsuo Sakka, Naoya Nishi.
  Langmuir. 41 [27] (2025) 17973-17981 10.1021/acs.langmuir.5c01819

• Microtubules Disruption Alters the Cellular Structures and Mechanics Depending on Underlying Chemical Cues.

  Shimaa A. Abdellatef, Hongxin Wang, Jun Nakanishi.
  Small. 21 [13] (2025) 2312282 10.1002/smll.202312282

• Highly Deformable Phototunable Viscoelastic Fluid Interface Modulates Cellular Adaptive Wetting Behavior.

  Junhong Zhou, Hongxin Wang, Jun Nakanishi.
  Advanced Functional Materials. 35 [7] (2025) 2414534 10.1002/adfm.202414534

• From LCST to crystals: structural modulation of ionic liquids drives the phase transition of poly(2-isopropyl-2-oxazoline).

  Mai Kamiyama-Ueda, Takeshi Ueki, Yuji Kamiyama, Ryota Tamate, Keisuke Watanabe, Yukiteru Katsumoto
  Chemical Communications. 61 [49] (2025) 8843-8846 10.1039/d5cc01017a

• In situ formation of ultrahigh molecular weight polymers in highly concentrated electrolytes and their physicochemical properties.

  Yuji Kamiyama, Takeshi Ueki, Ryota Tamate
  Soft Matter. 21 [8] (2025) 1471-1478 10.1039/d4sm01248h

• Enlightening the effect of strontium in the BiVO₄–TiO₂ diphase composites for dielectric devices.

  K. Yukesh Kumar, N. Sivakumar, G. M. Bhalerao, G. Anbalagan, Kentaro Tashiro, Ali Alsulmi
  Journal of Materials Science: Materials in Electronics. 36 [18] (2025) 1104 10.1007/s10854-025-15208-w

• Photoresponsive surface engineering using 2-nitrophenethyl-based heterobifunctional linkers and silane coupling agents.

  Shota Yamamoto, Michiko Ito, Daiki Sato, Tomoya Yamada, Kazuo Yamaguchi
  Colloids and Surfaces A: Physicochemical and Engineering Aspects. 727 (2025) 138311 10.1016/j.colsurfa.2025.138311

2024

• Dynamic cell photo-manipulation technology for the molecular and mechanical regulation analyses of collective cell migration.

  Kazuhiro Tatematsu, Shota Yamamoto, Masao Kamimura, Kazuo Yamaguchi, Jun Nakanishi
  Talanta Open. 9 (2024) 100319 10.1016/j.talo.2024.100319

• Data-driven optimization of the in silico design of ionic liquids as interfacial cell culture fluids.

  Jun Nakanishi, Takeshi Ueki, Sae Dieb, Hidenori Noguchi, Shota Yamamoto, Keitaro Sodeyama
  Science and Technology of Advanced Materials. 25 [1] (2024) 2418287 10.1080/14686996.2024.2418287

• Reversible Solubility Switching of a Polymer Triggered by Visible‐Light Responsive Azobenzene Photochromism with Negligible Thermal Relaxation.

  Takeshi Ueki, Yuna Osaka, Kenta Homma, Shota Yamamoto, Aya Saruwatari, Hongxin Wang, Masao Kamimura, Jun Nakanishi
  Macromolecular Rapid Communications. 45 [22] (2024) 2400419 10.1002/marc.202400419

• Ultimately Adaptive Fluid Interfacial Phospholipid Membranes Unveiled Unanticipated High Cellular Mechanical Work

  Zhou Lu, Mizuki Tenjimbayashi, Junhong Zhou, Jun Nakanish
  Advanced Materials 36 [27] 2403396. 2024.

• Photoactivatable surfaces resolve the impact of gravity vector on collective cell migratory characteristics.

  Shinya Sakakibara, Shimaa A. Abdellatef, Shota Yamamoto, Masao Kamimura, Jun Nakanishi
  Science and Technology of Advanced Materials. 24 [1] (2023) 2206525 10.1080/14686996.2023.2206525

• Ionic Liquid Interface as a Cell Scaffold.

  Takeshi Ueki, Koichiro Uto, Shota Yamamoto, Ryota Tamate, Yuji Kamiyama, Xiaofang Jia, Hidenori Noguchi, Kosuke Minami, Katsuhiko Ariga, Hongxin Wang, Jun Nakanishi Advanced Materials. 36 [26] (2024) 2310105 10.1002/adma.202310105

• マトリックス誘起上皮間葉転換の研究のための動的細胞足場材料の開発

  山本 翔太, 中西 淳
  分析化学 73 [3] 103-109. 2024.

• Straightforward preparation of a tough and stretchable ion gel.

  Aya Saruwatari, Yuji Kamiyama, Akifumi Kawamura, Takashi Miyata, Ryota Tamate, Takeshi Ueki
  Soft Matter. 20 [38] (2024) 7566-7572 10.1039/d4sm00628c

• Homogeneous Polymer Network Ion Gels Based on Metal Ion-Complexation-Induced Cross-Linking in Ionic Liquids.

  Saori Takano, Itsuki Takubo, Takeshi Ueki, Kenta Fujii
  ACS Applied Polymer Materials. 6 [17] (2024) 10149-10153 10.1021/acsapm.4c01792

• Rheological Properties of Dense Particle Suspensions of Starches: Shear Thickening, Shear Jamming, and Shock Absorption Properties.

  Sadaki Samitsu, Ryota Tamate, Takeshi Ueki
  Langmuir. 40 [51] (2024) 26852-26863 10.1021/acs.langmuir.4c02920

• Effect of Liquid Properties on the Non-Newtonian Rheology of Concentrated Silica Suspensions: Discontinuous Shear Thickening, Shear Jamming, and Shock Absorbance.

  Sadaki Samitsu, Ryota Tamate, Takeshi Ueki
  Langmuir. 40 [46] (2024) 24241-24256 10.1021/acs.langmuir.4c01547

• Macroscopic chiral symmetry breaking in gelation of Fmoc-amino acids: homochiral selective secondary nucleation promoted by the choice of solvent or stirring.

  Kentaro Tashiro
  Nanoscale. 16 [47] (2024) 21761-21766 10.1039/d4nr04011b

• Mapping stress inside living cells by atomic force microscopy in response to environmental stimuli

  Hongxin Wang, Han Zhang, Ryo Tamura, Bo Da, Shimaa A. Abdellatef, Ikumu Watanabe, Nobuyuki Ishida, Daisuke Fujita, Nobutaka Hanagata, Tomoki Nakagawa, Jun Nakanishi.
  Science and Technology of Advanced Materials 24 [1] 2265434. 2023.

• Functional oligo- and polypeptide assemblies for photochemical, optical and electronic applications.

  Yohei Yamamoto, Wey Yih Heah, Kentaro Tashiro
  Materials Horizons. 11 [14] (2024) 3203-3212 10.1039/d4mh00218k

2023

• Mapping stress inside living cells by atomic force microscopy in response to environmental stimuli

  Hongxin Wang, Han Zhang, Ryo Tamura, Bo Da, Shimaa A. Abdellatef, Ikumu Watanabe, Nobuyuki Ishida, Daisuke Fujita, Nobutaka Hanagata, Tomoki Nakagawa, Jun Nakanishi
  Science and Technology of Advanced Materials 24 [1] 2265434. 2023

• Photoactivatable surfaces resolve the impact of gravity vector on collective cell migratory characteristics

  Shinya Sakakibara, Shimaa A. Abdellatef, Shota Yamamoto, Masao Kamimura, Jun Nakanishi
  Science and Technology of Advanced Materials 24 [1] 2206525. 2023

• Growth and Migration Blocking Effect of Nanaomycin K, a Compound Produced by Streptomyces sp., on Prostate Cancer Cell Lines In Vitro and In Vivo

  Yuto Hirata, Katsumi Shigemura, Michika Moriwaki, Masato Iwatsuki, Yuki Kan, Tooru Ooya, Koki Maeda, Youngmin Yang, Takuji Nakashima, Hirotaka Matsuo, Jun Nakanishi, Masato Fujisawa
  Cancers 15 [10] 2684. 2023.

• Manipulating the Dynamic Adaptivity of a Fluid Interface to Maintain the Multipotency of Mesenchymal Stromal Cells

  Wenyan Lyu, Wei Hu, Jiaming Shi, Jieman Chen, Jingwen Song, Qindan Zhang, Xuefeng Yuan, Dairui Li, Jun Nakanishi, Xiaofang Jia
  Advanced Healthcare Materials 12 [24] 2300666. 2023.

• Polarity Does Not Matter: Molecular Weight Reverses the Photoisomerization‐Induced Phase Separation of an Azobenzene‐Bearing Polymer

  Kenta Homma, Alice C. Chang, Shota Yamamoto, Takeshi Ueki, Jun Nakanishi
  Macromolecular Rapid Communications 2300118. 2023.

• Mechanistic investigation into selective cytotoxic activities of gold nanoparticles functionalized with epidermal growth factor variants

  Aiwen Zhang, Shimaa A. Abdellatef, Jun Nakanishi
  Analytical Sciences . 2023.

• Adaptive Ion‐Gel: Stimuli‐Responsive, and Self‐Healing Ion Gels

  Ryota Tamate, Takeshi Ueki
  The Chemical Record e202300043. 2023.

• Investigation on p-nitrobenzylidene-p-phenylamineaniline: An organic optical single crystal developed by solution route for optoelectronic devices

  N. Sivakumar, K. Tashiro, Ali Alsulmi, R. Jayavel
  Optical Materials 143 114173. 2023.

• Mixed Conductive, Injectable, and Fluorescent Supramolecular Eutectogel Composites

  Miryam Criado‐Gonzalez, Nuria Alegret, Alejandro M. Fracaroli, Daniele Mantione, Gregorio Guzmán‐González, Rafael Del Olmo, Kentaro Tashiro, Liliana C. Tomé, Matias L. Picchio, David Mecerreyes
  Angewandte Chemie International Edition 62 [26] e202301489. 2023.

• 1D Supramolecular Assemblies That Crystallize and Form Gels in Response to the Shape-Complementarity of Alcohols

  Alejandro M. Fracaroli, Girishma Grover, Hiroyoshi Ohtsu, Masaki Kawano, Felipe Gándara, Rita H. de Rossi, Richard G. Weiss, Kentaro Tashiro
  Langmuir. 2023.

• Drycells: Cell‐Suspension Micro Liquid Marbles for Single‐Cell Picking

  Mizuki Tenjimbayashi, Shota Yamamoto, Koichiro Uto
  Advanced Materials 35 [30] 2300486. 2023.

2022

• Adaptive liquid interfaces induce neuronal differentiation of mesenchymal stem cells through lipid raft assembly

  Xiaofang Jia, Jingwen Song, Wenyan Lv, Jonathan P Hill, Jun Nakanishi, Katsuhiko Ariga, Nat Comm, 13: 1-10 (2022), DOI: 10.1038/s41467-022-30622-y

• Precise Tuning and Characterization of Viscoelastic Interfaces for the Study of Early Epithelial–Mesenchymal Transition Behaviors

  Alice Chinghsuan Chang, Koichiro Uto, Shimaa A Abdellatef, Jun Nakanishi, Langmuir, 38:, 5307–5314 (2022), DOI: 10.1021/acs.langmuir.1c03048

• Geometrical and Mechanical Nanoarchitectonics at Interfaces Bridging Molecules with Cell Phenotypes

  Jun Nakanishi, Shota Yamamoto, System-Materials Nanoarchitectonics, 275–286 (2022), 10.1007/978-4-431-56912-1_16

• Trends in biomaterials in Japan

  Jun Nakanishi, Mitsuhiro Ebara, Sci. Technol. Adv. Mater., 22: 808 (2021), DOI: 10.1080/14686996.2021.1969097

• Improved anti-cancer effect of epidermal growth factor-gold nanoparticle conjugates by protein orientation through site-specific mutagenesisImproved anti-cancer effect of epidermal growth factor-gold nanoparticle conjugates by protein orientation through site-specific mutagenesis

  Aiwen Zhang, Jun Nakanishi, Science and Technology of Advanced Materials, 22:616-626 (2021), DOI: 10.1080/14686996.2021.1944783

• Design of azobenzene-bearing hydrogel with photoswitchable mechanics driven by photo-induced phase transition for in vitro disease modeling

  Kenta Homma, Alice C Chang, Shota Yamamoto, Ryota Tamate, Takeshi Ueki, Jun Nakanishi, Acta Biomaterialia, 132: 103-113 (2021), DOI: 10.1016/j.actbio.2021.03.028

• Viscoelastically tunable substrates elucidate the interface-relaxation-dependent adhesion and assembly behaviors of epithelial cells

  Alice Chinghsuan Chang, Koichro Uto, Kenta Homma, Jun Nakanishi, Biomaterials, 274: 120861 (2021), DOI: 10.1016/j.biomaterials.2021.120861

• Analytical Biomaterials

  Takahito Oshiro, Jun Nakanishi, Tamotsu Zako, Mizuo Maeda, Takahito Ohshiro, Anal. Sci., 37: 649 (2021), DOI: 10.2116/analsci.GE2105

• Nanaomycin K inhibited epithelial mesenchymal transition and tumor growth in bladder cancer cells in vitro and in vivo

  Koichi Kitagawa, Katsumi Shigemura, Aya Ishii, Takuji Nakashima, Hirotaka Matsuo, Yoko Takahashi, Satoshi Omura, Jun Nakanishi, Masato Fujisawa, Sci. Rep., 11: 1-10 (2020), DOI: 10.1038/s41598-021-88741-3

2020

• Large-Area Aligned Fullerene Nanocrystal Scaffolds as Culture Substrates for Enhancing Mesenchymal Stem Cell Self-Renewal and Multipotency

  J. Song, X. Jia*, K. Minami, J. P. Hill, J. Nakanishi, L. K. Shrestha, and K. Ariga*, ACS Appl. Nano Mater., 7: 6497-6506 (2019), DOI: 10.1021/acsanm.0c00973.

• Adaptive Liquid Interfacially Assembled Protein Nanosheets for Guiding Mesenchymal Stem Cell Fate

  X. Jia*, K. Minami, K. Uto, A. C. Chang, J. P. Hill, J. Nakanishi*, and K. Ariga*, Adv. Mater., 32: 1905942 (2020). DOI: 10.1002/adma.201905942

2019

• A facile assay of epithelial-mesenchymal transition based on cooperativity quantification of cellular autonomous motions

  S. Yamamoto, T. Miyama, T. Komoda, M. Sugawara, M. Nonomura, and J. Nakanishi*, Anal. Sci., 36: 263-268 (2020). DOI: 10.2116/analsci.19P233.

• Nanaomycin K, a new epithelial-mesenchymal transition inhibitor produced by the actinomycete “Streptomyces rosa subsp. notoensis

  H. Matsuo, J. Nakanishi, Y. Noguchi, K. Kitagawa, K. Shigemura, T. Sunazuka, Y. Takahashi, S. Omura, T. Nakashima,* J. Biosci. Bioeng., 129: 291-295 (2020). DOI: 10.1016/j.jbiosc.2019.09.007.

• Photoactivatable hydrogel interfaces for resolving the interplay of chemical, mechanical, and geometrical regulation of collective cell migration

  S. Yamamoto, K. Okada, N. Sasaki, A. Chang, K. Yamaguchi, J. Nakanishi*, Langmuir, 35: 7459-7468 (2019). DOI: 10.1021/acs.langmuir.8b02371.

• Preparation of a Series of Photoresponsive Polymersomes Bearing Photocleavable a 2-nitrobenzyl Group at the Hydrophobic/Hydrophilic Interfaces and Their Payload Releasing Behaviors

  S. Yamamoto, T. Yamada, G. Kubo, K. Sakurai, K. Yamaguchi,* J. Nakanishi*, Polymers, 11: 1254 (2019). DOI: 10.3390/polym11081254.

• Synthesis of Poly(N-vinylpyrrolidone)-Based Polymer Bottlebrushes by ATRPA and RAFT Polymerization: Toward Drug Delivery Application

  Y.S. Huang, J.K. Chen, S.W. Kuo, Y.A. Hsieh, S. Yamamoto, J. Nakanishi,* C.F. Huang*, Polymers, 11(6): 1079 (2019). DOI: 10.3390/polym11061079.

• Epidermal growth factor-nanoparticle conjugates change the activity from anti-apoptotic to pro-apoptotic at membrane rafts

  Yamamoto, Y. Iwamaru, Y. Shimizu, Y. Ueda, M. Sato, K. Yamaguchi, J. Nakanishi*, Acta Biomaterialia, 88: 383-391 (2019). DOI: 10.1016/j.actbio.2019.02.026.

• Modulation of Mesenchymal Stem Cells Mechanosensing at Fluid Interfaces by Tailored Self-Assembled Protein Monolayers

  X. Jia,* K. Minami, K. Uto, A. C. Chang, J. P. Hill, T. Ueki, J. Nakanishi,* K. Ariga*, Small, 15: 1804640 (2019). DOI: 10.1002/smll.201804640.

2018

• Nanaomycin I and J: new nanaomycins generated by mycothiol-mediated compounds from “Streptomyces rosa subsp. notoensis” OS-3966

  H. Matsuo, Y. Noguchi, A Také, J. Nakanishi, K. Shigemura, T. Sunazuka, Y. Takahashi, S. Ōmura, and T. Nakashima*, J. Biosci. Bioeng., 127: 549-553 (2019). DOI: 10.1016/j.jbiosc.2018.10.013.

• An application of photoactivatable substrate for the evaluation of epithelial-mesenchymal transition inhibitors

  J. Nakanishi,* K. Sugiyama, H. Matsuo, Y. Takahashi, S. Ōmura, and T. Nakashima, Anal. Sci., 35: 65-70 (2019). DOI: 10.2116/analsci.18SDP07.

• Chapter 18: Mechanobiology

  J. Nakanishi,* Materials Nanoarchitectonics, K. Ariga, M. Ebara Ed., Wiley (2018). DOI: 10.1002/9783527808311.ch18.

• A dynamic biomaterial based on a 2-nitrobenzyl derivative with a tert-butyl substituent at the benzyl position: rapid response and minimized phototoxicity

  S. Yamamoto, H. Ikegami, K. Yamaguchi,* and J. Nakanishi*, ChemPhotoChem, 2: 786-790 (2018). Selected as a Front Cover. DOI: 10.1002/cptc.201800087.

• Photoactivatable substrates for systematic study of the impact of an extracellular matrix ligand on appearance of leader cells in collective cell migration

  S. A. Abdellatef and J. Nakanishi,* Biomaterials, 169: 72-84 (2018). DOI: 10.1016/j.biomaterials.2018.03.045.

2017

• Suppression of Myogenic Differentiation of Mammalian Cells Caused by Fluidity of a Liquid-Liquid Interface

  K. Minami, T. Mori, W. Nakanishi, N. Shigi, J. Nakanishi, J. P. Hill, M. Komiyama, and K. Ariga,* ACS Appl. Mater. Interf., 9: 30553-30560 (2017). DOI: 10.1021/acsami.7b11445.

• Nanaomycin new analog, nanaomycin H

  T. Nakashima,* T. Kimura, R. Miyano, H. Matsuo, T. Hirose, A. Kimishima, K. Nonaka, M. Iwatsuki, J. Nakanishi, Y. Takahashi, and S. Ōmura, J. Biosci. Bioeng., 123: 765-770 (2017). DOI:10.1016/j.jbiosc.2017.01.011.

• Photoactivatable Substrates: A Material-based Approach for Dissecting Cell Migration

  J. Nakanishi,* Chem. Rec., 17 (6): 611-621 (2017). DOI:10.1002/tcr.201600090.

2016

• Facile Preparation of Photoactivatable Surfaces with Tuned Substrate Adhesiveness

  Y. Shimizu, M. Kamimura, S. Yamamoto, S. A. Abdellatef, K. Yamaguchi, and J. Nakanishi,* Anal. Sci., 32: 1183-1188 (2016). DOI:10.2116/analsci.32.1183.

• Past, Present, and Future of Mechanobiology: from the Viewpoint of Biomaterial Researcher

  J. Nakanishi,* M. Ebara, and C. Yoshikawa, J. Jpn. Soc. Biomater. (Japanese), 34 (2): 106-111 (2016).

• What Are Emerging Concepts and Challenges in NANO?: Nanoarchitectonics, Hand-Operating Nanotechnology, and Mechanobiology

  K. Ariga,* K. Minami, M. Ebara, and J. Nakanishi, Polymer J., 48, 371-389 (2016). DOI:10.1038/pj.2016.8.

• Estradiol-tethered micropatterned surfaces for the study of estrogenic non-genomic pathways

  B. Qi, Y. Shimizu, J. Nakanishi,*, and F. M. Winnik,* Chem. Commun., 52: 10056-10059 (2016). DOI:10.1039/C6CC03899A.

• Methods for Measuring Forces in Cellular Mechanobiology

  J. Nakanishi,* Buseki (Japanese), (1), 25-26, (2016).

• Reduced Adhesive Ligand Density in Engineered Extracellular Matrices Induces an Epithelial-Mesenchymal-Like Transition

  S. Marlar, S. A. Abdellatef, and J. Nakanishi*, Acta Biomaterialia, 39: 106-113 (2016). DOI:10.1016/j.actbio.2016.05.006.

• 3.3 – Cell Manipulation Technologies

  J. Nakanishi,* Biomaterials Nanoarchitectonics, M. Ebara Ed. Elsevier (2016). DOI: 10.1016/B978-0-323-37127-8.00008-X.

• Dynamic Control of Cell Adhesion on a Stiffness-Tunable Substrate for Analyzing the Mechanobiology of Collective Cell Migration

  M. Kamimura, M. Sugawara, S. Yamamoto, K. Yamaguchi, and J. Nakanishi*, Biomater. Sci., 4: 933-937 (2016). Selected as an Outside Cover. DOI:10.1039/C6BM00100A.