We would like to welcome you all to the "Third International Symposium for Young Organic Chemists (3rd ISYOC)", which will be held at the Organic Nanomaterials Center (ONC), National Institute for Materials Science (NIMS), Tsukuba, Japan, in March 3-4, 2011.

The symposium focuses on new trends in organic chemistry, including polymer science, coordination chemistry, supramolecular chemistry, biochemistry, colloids and interfaces. It aims to provide a great opportunity for interdisciplinary discussion between young organic chemists on all aspects of Organic Nanomaterials.

The technical program will include 14 distinguished invited lectures in the following advanced research topics:

The main purpose of the symposium is to give the participants an opportunity to discuss ideas and experimental results with other young organic chemists and to stimulate the introduction of novel concepts for materialization based on Organic Nanomaterials. It is expected that during the symposium each young researcher will get a new perspective on their own research work. We hope all participants will benefit from the lectures and discussion during this symposium.

The other important mission of the symposium is to establish a worldwide organic chemists network, which includes members of the Organic Nanomaterials Center (ONC) at NIMS. The ONC, which was inaugurated in April 2006 within the National Institute for Materials Science (NIMS), covers a wide range of research on nanomaterials with tailored structures and functions including dendrimers, supermolecules, artificially-designed proteins, inorganic clusters, polymers, etc., aiming at providing useful materials for society.

See also,

Tentative Scientific Program

March 3 (Thu)

Opening Remarks


Kazunori SUGIYASU (Macromolecules Group, ONC, NIMS)

Session 1: Nanomaterials and Interface

Chair Person: Takashi NAKANISHI (Macromolecules Group, ONC, NIMS)


PresenterSota SATO Department of Applied Chemistry, School of Engineering, The University of Tokyo

"Magnetic Alignment of a Small Molecule Introduced by an Aligning Host"

Residual dipolar coupling (RDC) is observed by NMR for molecules orienting to magnetic field in solution and useful for 3D structural analysis. The applications to biomacromolecules are intensely investigated, but there is a limited number of aligning methods for small molecules. We found that a hollow complex with stacked aromatic rings diamagnetically oriented and showed RDC. Guest inclusion within the host complex introduced RDC for the guest, which is otherwise RDC-silent. The combination of designable host-guest chemistry and RDC analysis will serve as a new structural determination tool for small molecules.


PresenterKazukuni TAHARA Division of Frontier Materials Science, Graduate School of Engineering Science, Osaka University

"Two-Dimensional Porous Molecular Networks of Dehydrobenzo[12]annulenes at the Liquid/Solid Interface: Structural Control and Reactivity"

Construction of two-dimensional (2D) molecular networks on solid surfaces based on self-assembly is a subject of intense interest owing to the perspective of various applications in the field of nanoscience and nanotechnology. We have been engaging STM investigation of 2D molecular networks of dehydrobeno[12]annulene (DBA) derivatives at a liquid/solid interface. In this talk, recent progress about formation and functionality of 2D porous molecular networks formed by precisely designed DAB derivatives will be presented. In particular, I will focus an in-situ photoisomerization of azobenzene containing DBA derivative toward a size switching of network pore.


PresenterAnirban BANDYOPADHYAY Advanced Scanning Probe Microscopy Group, Advanced Nano Characterization Center, National Institute for Materials Science (NIMS)

"How can we solve a problem physically on an assembly of organic molecule: A journey towards realizing a practical “nano-brain”"

Several molecular machines are invented to solve three bottlenecks of human civilization, build nano-factories alleviating energy crisis, create nano-surgeons for blood-less, fatal-less surgery inside our body and build a creative and intelligent computer. Unless somebody/something is there at the nano-scale to control large number of such machines, instruct what to do, what not to, the machines invented in the last two decades would continue to face criticism for remaining in beaker forever. Therefore, all three singularities can be resolved with a nano-brain. Unfortunately, futurists and molecular engineers have remained silent on the essentiality of any such device. Our recent invention of 16-bit parallel processor operating in room temperature was a first step in this direction (PNAS-2008). Providing an operating platform for eight worlds finest machines, nano-brain justified that chemists working on a future molecular society are not daydreamers.

Our nano-brain is a future generation material that grows by itself. Decades old phenomenon, self-assembly is used to build decision-making architecture and thus a new world of materials science is opened before us. The reason is that, we start from one molecule and the ultimate information-processing machine that can take 4 billion decisions is built by itself. Till now, historically, self-assembly was used to grow an architecture that can do only one job, that is processing one decision. However, now, it is just a molecular material that collectively processes billions of decisions.


Coffee Break

Session 2: Biomaterials and Biochemistry

Chair Person: Kentaro TASHIRO (Riticular Group, MANA, NIMS)


PresenterYan XU RCAST, The University of Tokyo

"To Reveal Telomere's Mysterious by Chemical Approaches"

Telomeres are essential structures at the ends of all eukaryotic chromosomes. Human telomeres play an important role in critical processes underlying genome stability, cancer, and aging, and their importance was recognized by the 2009 Nobel Prize in Physiology or Medicine. In recent studies, using chemical approaches, we elucidated structure and function of human telomere DNA/RNA and developed a number of novel approaches to target human telomere for the treatment of cancer. In this talk, I will review our recent studies on human telomere DNA and RNA, providing an overview of advances in understanding the structures and functions of human telomere. I will also focus on our current efforts on developing various chemical approaches to targeting human telomere for the treatment of cancer.


PresenterMasato IKEDA Department of Synthetic Chemistry & Biological Chemistry, Graduate School of Engineering, Kyoto University

"Supramolecular Design of Nano-and Micro-Materials"

Supramolecular and molecular design of materials has a significant impact on nanotechnology and biotechnology. In particular, supramolecular hydrogels (a solid, jelly-like material) comprising networks of self-assembled supramolecular nanofibers of low-molecular-weight molecules has attracted growing interest as process-able, macroscopic soft matrix. Here I report on the construction of intriguing supramolecular nano- and micro-materials, such as fluidic nano-rail network for mass transport, fluorescent sensor materials for polyions of biological significance, and cell-responsive substance release matrices, which utilize unique properties of the supramolecular nanofibers and hydrogels developed by design at molecular and supramolecular level.


PresenterShinsuke SANDO INAMORI Frontier Research Center, Kyushu University

"ChemBio Hybrid Technologies for In Cell and In Vivo Chemistry"

Living systems are composed of a variety of chemical events. The primary scientific objective of our research is to understand the dynamic chemical function of biological system at the molecular level. Toward this objective, one of the most promising approaches is to analyze such chemical events directly. We have been challenging to develop new technologies for in-cell and in-vivo analysis of such chemical events. In this presentation, I will talk about our research activities, especially focusing on in-cell nucleic acid analysis based on organic and supramolecular chemistry. In addition, I will also introduce recent progresses on in vivo analysis of chemical reactions.


Panel Discussion / Optional Group Meeting

March 4 (Fri)

Session 3: Conjugated Molecules and Polymers

Chair Person: Masayuki TAKEUCHI (Macromolecules Group, ONC, NIMS)


PresenterAtsushi WAKAMIYA Institute for Chemical Research, Kyoto University

"The Chemistry of B–B Bond-Containing Polycyclic π-Electron Systems"

Incorporation of electron deficient boron atom(s), bearing vacant p-orbital(s), into a π-conjugated cyclic skeleton enables the formation of a unique π system whose neutral and anionic species are isoelectronic to its cationic and neutral carbon analogues, respectively. In the case that a B–B bond is introduced into a polycyclic skeleton, how does this bond participate into the π-conjugation in both its neutral and dianionic species? As a model system, we synthesized dithieno-fused 1,2-dihydro-1,2-diborin derivatives, in which a B–B unit is incorporated into a 2,2’-bithiophene framework. The X-ray structural analysis and the theoretical calculations revealed that while the neutral compound has a planar 1,2-diborin ring with 4π electron antiaromaticity, the dianionic species has a characteristic peripheral π-conjugation through the B–B bond with 14π electrons. In this presentation, a counter cation effect on the photophysical properties of the dianion will also be reported.


PresenterKazunori SUGIYASU Macromolecules Group, Organic Nanomaterials Center, NIMS

"Designing Space around π-Conjugated Polymers: A Case of Polythiophene"

Insulated molecular wires (IMWs) are conjugated polymers molecularly covered with an insulating layer, which are structurally analogous to electric cords in nano-scale. Due to the “insulation” of the π-conjugated backbones, IMWs are expected to be applied to various optoelectronic applications and nanotechnology. Particularly intriguing are the examples based upon conducting polymers such as polypyrroles and polythiophenes, which are as of yet scarcely developed. A charge carrier confined within such one-dimensional transporting pathways not only leads to various electronic applications, but also enables elucidation of the mechanisms of conduction. Herein, we report on a self-threading polythiophene whose conducting molecular wire is sheathed within its own cyclic side chains. Notably, the covalently linked cyclic side chains enhance the effective conjugation length (ECL) of the interior polythiophene backbone, which results in an excellent intrinsic hole mobility.


Coffee Break

Chair Person: Taichi IKEDA (NIMS-MPI International Joint Laboratory)


PresenterTsuyoshi MICHINOBU Global Edge Institute, Tokyo Institute of Technology

"Click Postfunctionalization of Organic Semiconducting Polymers"

Click chemistry is the study of highly efficient addition reactions, which yield no byproducts. The most well-known click chemistry reaction is the copper(I)-catalyzed azide-alkyne cycloaddition reaction, which forms a triazole ring. Although this reaction has been widely used in the field of material science, it is difficult to improve optoelectronic properties of organic semiconducting polymers. To overcome this disadvantage, new types of click chemistry reaction were developed. For example, a quantitative addition reaction between electron-rich alkynes and a strong acceptor molecule, tetracyanoethylene, yields highly colored chromophores, namely donor-substituted 1,1,4,4-tetracyanobutadienes. These chromophores were readily introduced into a variety of organic semiconducting polymers by the postfunctionalization method for improvement of their optoelectronic properties


PresenterJunji SAKAMOTO Laboratory of Polymer Chemistry, Institute of Polymers, Department of Materials, ETH Zurich, Switzerland

"Synthesis of Two-Dimensional Polymers by Organic Chemistry Approaches"

In light of the considerable impact synthetic 2D polymers are expected to have on many fundamental and applied aspects of the natural and engineering sciences, it is surprising that these intriguing macromolecules still mark an almost empty space on the wish list of chemistry. Though numerous approaches have been reported over the last decades, the synthesis of a one-monomer-unit thick (better: thin), laterally infinite, free-standing unimolecular sheet with defined internal periodicity still remains a major challenge for chemists. We consider the rational design of monomers as key prerequisite for realizing their laterally periodic growth in a programmed manner. Polymerizations are conducted in bulk, in solution as well as at interfaces. The contribution will provide the state-of-the-art situation showing some concrete examples for these approaches leading to 2D polymers.



Session 4: Organic Materials: Basics to Applications

Chair Person: Kazunori SUGIYASU (Macromolecules Group, ONC, NIMS)


PresenterTaku Hasobe Department of Chemistry, Faculty of Science and Technology, Keio University and PRESTO, JST

"Construction of Functional Molecular Architectures for Optoelectronics"

Increased efforts to assemble dye molecules into desired structures have been made because of their extended p-electron conjugation. Recent developments in synthetic and supramolecular techniques have made it possible to precisely control and organize molecules at the nanometer level. Such strategies enable us to construct molecular assemblies for optoelectronics such as photovoltaics. In photovoltaic cells, the following three processes such as light-harvest, charge separation, and carrier transport are generally required. Therefore, construction of supramolecular assemblies possessing these three processes are interesting and promising for future electronic applications.

In this presentation, the focus is on our recent development of supramolecular architectures for optoelectronics. The details of preparation method, structural and photoelectrochemical properties will be discussed.


PresenterYuka KOBAYASHI Innovative Center of Nanomaterials Science for Environment and Energy (ICNSEE), NIMS

"New Carrier Generation in TTF-based Ammonium Salts"

Several salt-bridged hydrogen-bonding ammonium salts of tetrathiafulvalene (TTF) derivatives exhibit semiconducting behavior at RT. These salts spontaneously include TTF cation radical upon crystallization, inducing unexpected generation of carriers. Powder X-ray diffraction analysis reveals that these salts are supramolecular conductors, where TTF moieties self-assemble in one dimension by a helical columnar hydrogen-bonding network. Transport properties showed large deutration effects, clearly demonstrating a strong correlation between the carriers and the hydrogen-bonding protons in these materials. Mechanism of the hole-injection and some physical properties of these conductors are discussed.


PresenterTsuyohiko FUJIGAYA Associate Professor, Institute for Advanced Study, Kyushu University

"Hierarchic Functionalization of Carbon Nanotubes based on Non-covalent Assembly for Fuel Cell Electrocatalyst"

Carbon nanotube (CNTs) functionalization through physical adsorption emerged as an important subject for the material science field. We found the polybenzimidazoles (PBIs) can non-covalently wrap the CNT via strong π-π interaction onto the CNT surface and realize an effective platinum (Pt) loading due to the coordination of Pt ion to aromatic nitrogen in PBIs. Activations of ion-conductivity of the PBI-wrapping layer by doping of either phosphoric acid or potassium hydroxide impart the proton- or hydroxide-conductivity, respectively, to the composite. We successfully fabricated the proton-conductive and hydroxide-conductive polymer electrolyte fuel cells using the obtained composites and found the both cells showed excellent performances.


PresenterKeisuke TAJIMA Department of Applied Chemistry, School of Engineering, The University of Tokyo and JST-ERATO Hashimoto Light Energy Conversion Project

"Polymer Synthesis for Nanostructured Organic Photovoltaics"

Polymer photovoltaic devices based on “bulk heterojunction” using a mixture of electron donor and acceptor materials in thin films have been extensively studied these days. Although relatively high power conversion efficiency have been reported by this approach, it is necessary for further improvement to precisely construct the stable, reproducible nanostructures that are suitable for the efficient charge separation and transport inside the films. For this purpose, it is highly desirable to utilize bottom-up approach such as self-organized formation of organic nanostructures. In the current presentation, some of our recent approaches for the control of the nanostructures are introduced from the viewpoint of the polymer synthesis.

Concluding Remarks

Izumi ICHINOSE (Managing Director, ONC, NIMS)


Please e-mail to Dr. Kazunori SUGIYASU (SUGIYASU.Kazunori@nims.go.jp) for registration.

The participation is free of charge.


NIMS Location map


Organic Nanomaterials Center (ONC),
National Institute for Materials Science (NIMS),
1-1 Namiki, Tsukuba, Ibaraki, 305-0044, Japan

How To Access : English / 日本語

Organizing Committee


Dr. Kazunori SUGIYASU (SUGIYASU.Kazunori@nims.go.jp) ISYOC Secretariat

Organic Nanomaterials Center (ONC),
National Institute for Materials Science (NIMS),
1-2-1 Sengen, Tsukuba, 305-0047, Japan.

TEL : +81-29-859-2110
FAX : +81-29-859-2101