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Koichiro Uto

ICYS-NAMIKI Researcher


    • Specialty:

      • Shape-memory polymer
        Polymer and organic synthesis
        • Academic degree:

          • Ph.D., Kagoshima University, Japan (March, 2010)

Educational & Research History

2016 Oct - Present
2016 Oct - Present
AMED-PRIME, Japan Agency for Medical Research and Development
2015 Apr - 2016 Sep
JSPS Postdoctoral Fellow for Research Abroad, University of Washington (Prof. Deok-Ho Kim and Prof. Cole A DeForest)
2010 Apr - 2015 Mar
Postdoctoral researcher, MANA, NIMS
2010 Apr - 2013 Mar
Joint resercher First Program (Prof. Teruo Okano)
2007 Apr - 2010 Mar
Ph.D., Kagoshima University, Japan

Research Interests

Dynamic cell culture platforms for probing cellular behaviors (Material-based mechanobiology)
Light-responsive cell culture platforms for dynamic mechanobiology
Bio-mimetic/inspired materials for tissue engineering and regenerative medicine


  • 2015 Mar: Outstanding Award for Poster Presentation (3rd Hoffman Family Symposium)
  • 2014 Nov: FON’14 Excellent Poster Award (2nd International Symposium on the Functionality of Organized Nanostructures 2014)
  • 2014 Mar: Excellent Poster Presentation Award (MANA International Symposium 2014)
  • 2014 Jan: Best Poster Award (Tsukuba Biomedical Engineering Forum 2014)
  • 2012 Nov: Young Scientist Poster Award (Symposium 2012 of the Japanese Society for Biomaterials)
  • 2012 Jul: Incentive Award for Young Scientist (6th Conference of the Nano Biomedical Society)
  • 2012 Jan: Best Poster Award (Tsukuba Biomedical Engineering Forum 2012)
  • 2006 Jul: Incentive Award for Young Scientist (45th Join Symposium on The Chemical Society of Japan in Kyushu Branch)

Selected Papers

  1. Dynamically Tunable Cell Culture Platforms for Tissue Engineering and Mechanobiology
    K.Uto, J. H. Tsui, C. A. DeForest, D.-H. Kim
    Progress in Polymer Science, in press. <doi: http://dx.doi.org/doi:10.1016/j.progpolymsci.2016.09.004>
  2. Substrate fluidity regulates cell adhesion and morphology on poly(e-caprolactone)-based materials
    K. Uto, S. S. Mano, T. Aoyagi, M. Ebara
    ACS Biomaterials Science & Engineering, 2(3), 446-453 (2016) <doi: 10.1021/acsbiomaterials.6b00058>
  3. Hybridizing poly(e-caprolactone) and plasmonic titanium nitride nanoparticles for broadband photoresponsive shape memory films
    S. Ishii*, K. Uto*, E. Niiyama, M. Ebara, T. Nagao (*; contributed equally)
    ACS Applied Materials & Interfaces, 8(8), 5634-5640 (2016) <doi: 10.1021/acsami.5b12658>
  4. Spatiotemporal control of cardiac anisotropy using dynamic nanotopographic cues
    P. Y. Mengsteab*, K. Uto*, A. S. T. Smith, S. Frankel, E. Fisher, Z. Nawas, J. Macadangdang, M. Ebara, D.-H. Kim (*; contributed equally)
    Biomaterials, 86, 1-10 (2016) <doi:10.1016/j.biomaterials.2016.01.062>
  5. Fluidity of biodegradable substrate regulates carcinoma cell behaviour: A novel approach to cancer therapy
    S. S. Mano, K. Uto, T. Aoyagi, M. Ebara
    AIMS Materials Science, 3(1), 66-82 (2016) <doi: 10.3934/matersci.2016.1.66>
  6. Inactivated Sendai Virus (HVJ-E) Immobilized Electrospun Nanofiber for Cancer Therapy
    T. Okada, E. Niiyama, K. Uto, T. Aoyagi, M. Ebara
    Materials, 9(1), 12 (2016) <doi: 10.3390/ma9010012>
  7. Biomimetic Approach to Hormone Resistant Prostate Cancer Cell Isolation Using Inactivated Sendai Virus (HVJ-E)
    T. Okada, K. Uto, T. Aoyagi, M. Ebara
    Biomaterials Science, 4, 96-103 (2016) <doi: 10.1039/C5BM00375J> (selected as “Front Cover”)
  8. Biodegradable Nanofiber for Delivery of Immunomodulating Agent in the Treatment of Basal Cell Carcinoma”
    R. Garrett, E. Niiyama, Y. Kotsuchibashi, K. Uto, M. Ebara
    Fibers, 3, 478-490 (2015) <doi: 10.3390/fib3040478>
  9. Simultaneous Drug and Gene Delivery from the Biodegradable Poly(-caprolactone) Nanofibers for the Treatment of Liver Cancer
    H.-L. Che, H. J. Lee, K. Uto, M. Ebara, W. J. Kim, T. Aoyagi, I. K. Park
    J. Nanosci. Nanotech., 15, 7971-7975 (2015) <doi: 10.1166/jnn.2015.11233>
  10. “Implementation of poly(ε-caprolactone) sheet-based shape-memory microvalves into plastic-based microfluidic devices”
    C. Jiang, K. Uto, M. Ebara, T. Aoyagi, T. Ichiki
    Jpn. J. Appl. Phys., 54, 06FN02 (2015) <doi: 10.7567/JJAP.54.06FN02>
  11. pH and glucose responsive nanofibers for the reversible capture and release of lectins
    W. Yinan, Y. Kotsuchibashi, K. Uto, M. Ebara, T. Aoyagi, Y. Liu, R. Narain
    Biomaterials Science, Biomaterials Science, 3, 152-162 (2015) <doi: 10.1039/C4BM00269E>