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Polymeric Biomaterials Group

Our group focuses on the development of innovative polymeric biomaterials by controlling biological reactions at the interface between materials and biological components occurring from acute stage to chronic stage for medical treatment. Our activities also include molecular design, synthesis of polymeric biomaterials and analysis of the interactions between polymer-based materials and biological components, such as cells and tissues, in order to establish feedback loop for development of innovative polymeric biomaterials such as bioadhesives. The goal of our researches is to apply the innovative biomaterials for clinical fields in collaboration with medical/dental institutes and companies.

Specialized Research Field

Research Field

Based on the cell/tissue adhesive science and biointerface science, we perform fundamental researches on innovative biomaterials that induce tissue regeneration/repair by themselves. We also collaborate with medical/dental institutes and companies in order to utilize obtained knowledge and developed materials for clinical applications.

Biocompatible High Strength Tissue Adhesive

 An innovative tissue adhesive composed of hydrophobically-modified Alaska pollock gelatin and poly(ethylene glycol)-based crosslinker has been developed. This adhesive can be applied for various surgical fields including cardiovascular and thoracic surgery.

"J Biomed Nanotechnol 2016, 12, 128-134." Image

J Biomed Nanotechnol 2016, 12, 128-134.

Development of Growth Factor-Free Tissue Adhesive Porous Films Singularly Capable of Promoting Angiogenesis

 Tissue adhesive porous films that promote angiogenesis without using growth factors have been developed. This film may contribute to tissue/organ engineering and regenerative medicine.

"Biomateirals 2015, 63, 14-23." Image

Biomateirals 2015, 63, 14-23.

Cell Adhesive

 Enzymatically-degradable and synthetic cell adhesive that can promote assembly of desired cells have been developed. Assembled cells showed greater cell functions as compared with cells without addition of cell adhesive. This material can be applied for organ engineering using various kinds of cells.

"Colloids Surfaces B 2013, 101, 223-227." Image

Colloids Surfaces B 2013, 101, 223-227.

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1-1 Namiki, Tsukuba, Ibaraki, 305-0044 JAPAN